Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006783 | 0.88 | TDP1 (0.49) | RAB9AKDM4ENPC1TDP1TP53 | |
| SCHEMBL28001171 | 0.81 | KDM4E (0.50) | KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL29503858 | 0.78 | PLAU (0.53) | RAB9AL3MBTL1NPC1CA12CA1 | |
| SCHEMBL1101140 | 0.78 | PLAU (0.53) | RAB9AL3MBTL1NPC1CA12CA1 | |
| SCHEMBL3306584 | 0.76 | SMN1; SMN2 (0.54) | RAB9AKDM4EL3MBTL1CA12CA1 | |
| SCHEMBL29056033 | 0.76 | GRM2 (0.47) | RAB9AKDM4ENPC1CA1CA2 | |
| SCHEMBL5250683 | 0.75 | RAB9A (0.42) | RAB9AKDM4EROCK2ROCK1CA12 | |
| SCHEMBL30006624 | 0.75 | NR3C2 (0.42) | KDM4EMAPTPLAU | |
| SCHEMBL1503239 | 0.74 | KDM4E (0.45) | RAB9AKDM4EL3MBTL1NPC1TDP1 | |
| SCHEMBL8092420 | 0.74 | KMT2A (0.54) | KDM4ENPC1ROCK2ROCK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808023-B | Method for preparing 3-aryl isoquinoline derivative | 四川大学 | 2022-10-21 | — | — | CN | disclosed |