Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119931 | 0.76 | KDM4E (0.49) | RAB9AKMT2AMAOBMEN1ROCK2 | |
| SCHEMBL5116129 | 0.76 | MAOB (0.48) | KMT2AMAOBMEN1ROCK2ROCK1 | |
| SCHEMBL30006842 | 0.75 | RAB9A (0.45) | RAB9AKMT2ACA12CA1CA2 | |
| SCHEMBL5118706 | 0.74 | MAOB (0.48) | RAB9AKMT2AMAOBMEN1ROCK2 | |
| SCHEMBL13729249 | 0.73 | HTR6 (0.50) | ALDH1A1IDO1LMNAKDM4E | |
| SCHEMBL5121466 | 0.73 | TDP1 (0.49) | KMT2AMAOBROCK2ROCK1HPGD | |
| SCHEMBL5128409 | 0.72 | MAOB (0.48) | KMT2AMAOBROCK2ROCK1HPGD | |
| SCHEMBL5119117 | 0.72 | MAOB (0.48) | KMT2AMAOBMEN1ROCK2ROCK1 | |
| SCHEMBL5123346 | 0.71 | HPGD (0.52) | RAB9AKMT2AMAOBMEN1HPGD | |
| SCHEMBL15458842 | 0.71 | EGLN1 (0.47) | RAB9AKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441734-B1 | DIHYDROXYPYRIMIDINE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-02-28 | — | — | EP | disclosed |