Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 8/20 | 0.53 |
| ▸ | BACE1 | P56817 | 4/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27092763 | 1.00 | KDM4E (0.64) | KDM4EGAAROCK2ROCK1MAPK1 | |
| SCHEMBL4664267 | 0.84 | KDM4E (0.56) | KDM4EGAAROCK2ROCK1MAPK1 | |
| SCHEMBL3138352 | 0.83 | ACHE (0.59) | KDM4EGAAMAPK1HRH3ACHE | |
| SCHEMBL5432812 | 0.82 | ACHE (0.69) | KDM4EGAAROCK2ROCK1HRH3 | |
| SCHEMBL16007611 | 0.82 | KDM4E (0.56) | KDM4EGAAMAPK1HRH3ACHE | |
| SCHEMBL19873872 | 0.80 | ALDH1A1 (0.49) | KDM4EGAAROCK2ROCK1MAPK1 | |
| SCHEMBL3359734 | 0.80 | DRD2 (0.71) | KDM4EGAAROCK2ROCK1HRH3 | |
| SCHEMBL19086771 | 0.79 | KDM4E (0.67) | KDM4EGAAMAPK1HRH3ACHE | |
| SCHEMBL1285665 | 0.78 | GRIN2B (0.58) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6160260 | 0.78 | HRH3 (0.61) | KDM4EGAAMAPK1HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323357-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-IMIDAZO[4,5-B]PYRIDIN-2-ONE AND/OR DERIVATIVES THEREOF | Siegfried AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022218811-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-IMIDAZO[4,5-B]PYRIDIN-2-ONE AND/OR DERIVATIVES THEREOF | SIEGFRIED AG (CH) | 2022-10-20 | — | — | WO | disclosed |