Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.53 |
| ▸ | SGK1 | O00141 | 1/20 | 0.53 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30007736 | 0.88 | CAMKK2 (0.57) | AXLCYP2C9CYP2C19CAMKK2SGK1 | |
| SCHEMBL30008314 | 0.87 | AXL (0.67) | AXLCYP2C9CYP2C19CAMKK2SGK1 | |
| SCHEMBL4119627 | 0.83 | AXL (0.61) | AXLCAMKK2SGK1AAK1 | |
| SCHEMBL4119636 | 0.82 | MAP4K1 (0.67) | AXLCYP2C19CAMKK2SGK1PAK1 | |
| SCHEMBL2891511 | 0.76 | CYP2C19 (0.70) | CYP2C9CYP2C19MAP2K1 | |
| SCHEMBL2891508 | 0.76 | CYP2C19 (0.72) | CYP2C9CYP2C19MAP2K1 | |
| Hydrochloric Acid SCHEMBL30007576 | 0.75 | AXL (0.54) | AXLCYP2C9CYP2C19CAMKK2SGK1 | |
| SCHEMBL16946570 | 0.75 | CAMKK2 (0.51) | AXLCYP2C9CYP2C19CAMKK2SGK1 | |
| SCHEMBL18238316 | 0.75 | CAMKK2 (0.51) | AXLCYP2C9CYP2C19CAMKK2SGK1 | |
| SCHEMBL7117672 | 0.75 | CYP2C9 (0.53) | CYP2C9CYP2C19CAMKK2SGK1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237922-A1 | ANTITUMOR COMPOUNDS BASED ON NITROGEN HETEROCYCLES AND USE THEREOF AS MEDICAMENTS | FAKULTNI NEMOCNICE HRADEC KRALOVE (CZ) | 2022-11-17 | — | — | WO | disclosed |