Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.67 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.50 |
| ▸ | SGK1 | O00141 | 1/20 | 0.50 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NEK1 | Q96PY6 | 4/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30007576 | 0.89 | AXL (0.54) | AXLCAMKK2SGK1AAK1PIK3CA | |
| SCHEMBL30007360 | 0.87 | AXL (0.72) | AXLCAMKK2SGK1AAK1MAP2K1 | |
| SCHEMBL4119627 | 0.80 | AXL (0.61) | AXLCAMKK2SGK1AAK1 | |
| SCHEMBL30007677 | 0.80 | AXL (0.50) | AXLCAMKK2SGK1AAK1PIK3CA | |
| SCHEMBL4119636 | 0.79 | MAP4K1 (0.67) | AXLCAMKK2SGK1CYP2C19 | |
| SCHEMBL30007734 | 0.79 | MAPK8 (0.45) | AXLCAMKK2PIK3CADYRK1A | |
| SCHEMBL30007804 | 0.78 | ALDH1A1 (0.46) | AXLCYP2C9CYP2C19 | |
| SCHEMBL2887279 | 0.78 | BRAF (0.59) | MAP2K1CYP2C9CYP2C19 | |
| SCHEMBL2887275 | 0.77 | CYP2C19 (0.59) | MAP2K1CYP2C9CYP2C19 | |
| SCHEMBL30007672 | 0.76 | PAK1 (0.53) | AXLCAMKK2PIK3CACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237922-A1 | ANTITUMOR COMPOUNDS BASED ON NITROGEN HETEROCYCLES AND USE THEREOF AS MEDICAMENTS | FAKULTNI NEMOCNICE HRADEC KRALOVE (CZ) | 2022-11-17 | — | — | WO | disclosed |