Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 14/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535625 | 1.00 | LDHA (0.45) | LDHAFYNMAP4K4KCNH2 | |
| SCHEMBL31265355 | 0.81 | FYN (0.62) | FYNKCNH2 | |
| SCHEMBL23535571 | 0.81 | FYN (0.64) | FYNKCNH2 | |
| SCHEMBL23535601 | 0.81 | FYN (0.62) | FYNKCNH2 | |
| SCHEMBL23535595 | 0.80 | FYN (0.47) | FYN | |
| SCHEMBL31265359 | 0.80 | FYN (0.70) | FYN | |
| SCHEMBL23535556 | 0.80 | FYN (0.70) | FYN | |
| SCHEMBL23535591 | 0.77 | FYN (0.57) | FYN | |
| SCHEMBL23535618 | 0.74 | TGFBR1 (0.42) | LDHAMAP4K4 | |
| SCHEMBL30006850 | 0.74 | TGFBR1 (0.42) | LDHAMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |
| EP-4077332-A1 | INHIBITORS OF LIN28 AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2022-10-26 | — | — | EP | disclosed |