Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529724 | 1.00 | MAPT (0.40) | MAPTKRASSLC9A1PDE4APDE4B | |
| SCHEMBL30761125 | 0.87 | MAPT (0.42) | MAPTSLC9A1MEN1KMT2APKM | |
| SCHEMBL23546510 | 0.84 | PDE4A (0.40) | MAPTKRASSLC9A1PDE4APDE4B | |
| SCHEMBL30007377 | 0.82 | SLC9A1 (0.42) | MAPTSLC9A1OPRM1MEN1KMT2A | |
| SCHEMBL29804193 | 0.78 | KRAS (0.37) | MAPTKRASSLC9A1PDE4APDE4B | |
| SCHEMBL23529808 | 0.78 | KRAS (0.41) | MAPTKRASSLC9A1PDE4APDE4B | |
| SCHEMBL1118681 | 0.76 | MAPT (0.47) | MAPTSLC9A1MEN1KMT2APKM | |
| SCHEMBL14662867 | 0.75 | OPRM1 (0.40) | MAPTSLC9A1OPRM1MEN1KMT2A | |
| SCHEMBL27087160 | 0.74 | SLC9A1 (0.42) | MAPTSLC9A1OPRM1MEN1KMT2A | |
| SCHEMBL30932761 | 0.73 | ABL1 (0.47) | MAPTSLC9A1MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076662-A1 | PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS | Novartis AG (CH) | 2022-10-26 | — | — | EP | disclosed |