Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14662867 | 0.84 | OPRM1 (0.40) | SLC9A1MAPTPKMALDH3A1HTR6 | |
| SCHEMBL30761125 | 0.84 | MAPT (0.42) | SLC9A1MAPTPKMALDH3A1HTR6 | |
| SCHEMBL27087160 | 0.83 | SLC9A1 (0.42) | SLC9A1MAPTPKMALDH3A1HTR6 | |
| SCHEMBL23529724 | 0.82 | MAPT (0.40) | SLC9A1MAPTPKMALDH3A1MEN1 | |
| SCHEMBL30007565 | 0.82 | MAPT (0.40) | SLC9A1MAPTPKMALDH3A1MEN1 | |
| SCHEMBL31411468 | 0.78 | SLC9A1 (0.42) | SLC9A1MAPTPKMHTR6MEN1 | |
| SCHEMBL23529742 | 0.75 | SLC9A1 (0.36) | SLC9A1MAPTPKMHTR6MEN1 | |
| SCHEMBL31156874 | 0.75 | SLC9A1 (0.48) | SLC9A1MAPTPKMALDH3A1MEN1 | |
| SCHEMBL1272465 | 0.75 | OPRD1 (0.45) | SLC9A1MAPTPKMALDH3A1MEN1 | |
| SCHEMBL1118681 | 0.75 | MAPT (0.47) | SLC9A1MAPTPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076662-A1 | PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS | Novartis AG (CH) | 2022-10-26 | — | — | EP | disclosed |