Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 5/20 | 0.39 |
| ▸ | SGK1 | O00141 | 3/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007692 | 0.87 | GSK3A (0.51) | GSK3AGSK3BPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL30007830 | 0.84 | DYRK1A (0.45) | GSK3AGSK3BPRKDCATMATR | |
| SCHEMBL29253947 | 0.81 | GSK3A (0.48) | GSK3AGSK3BPRKDCATMATR | |
| SCHEMBL30007738 | 0.79 | KDM5A (0.42) | GSK3AGSK3BPRKAG1PRKAA1PRKAB1 | |
| Hydrochloric Acid SCHEMBL30007576 | 0.79 | AXL (0.54) | CAMKK2SGK1AXLDYRK1A | |
| SCHEMBL29253946 | 0.78 | GSK3B (0.46) | GSK3AGSK3BDYRK1A | |
| SCHEMBL29253944 | 0.78 | GSK3B (0.46) | GSK3AGSK3BDYRK1A | |
| SCHEMBL30912725 | 0.78 | GSK3B (0.46) | GSK3AGSK3BDYRK1A | |
| SCHEMBL30912733 | 0.78 | GSK3B (0.46) | GSK3AGSK3BDYRK1A | |
| SCHEMBL30007248 | 0.77 | ATR (0.40) | GSK3BATRDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237922-A1 | ANTITUMOR COMPOUNDS BASED ON NITROGEN HETEROCYCLES AND USE THEREOF AS MEDICAMENTS | FAKULTNI NEMOCNICE HRADEC KRALOVE (CZ) | 2022-11-17 | — | — | WO | disclosed |