Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.37 |
| ▸ | CTSA | P10619 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | PRKACG | P22612 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | ACSL5 | Q9ULC5 | 1/20 | 0.31 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242930 | 1.00 | GABRA5 (0.37) | GABRA5CTSACNR1ROCK2ROCK1 | |
| SCHEMBL25687233 | 1.00 | GABRA5 (0.37) | GABRA5CTSACNR1ROCK2ROCK1 | |
| SCHEMBL30007230 | 0.93 | GABRA5 (0.36) | GABRA5CTSACNR1CYP2C9MAPK14 | |
| SCHEMBL23958645 | 0.93 | GABRA5 (0.36) | GABRA5CTSACNR1CYP2C9MAPK14 | |
| SCHEMBL25686195 | 0.93 | GABRA5 (0.36) | GABRA5CTSACNR1CYP2C9MAPK14 | |
| SCHEMBL30006737 | 0.93 | CNR1 (0.39) | GABRA5CTSACNR1ROCK2ROCK1 | |
| SCHEMBL25233253 | 0.93 | CNR1 (0.39) | GABRA5CTSACNR1ROCK2ROCK1 | |
| SCHEMBL25687231 | 0.93 | CNR1 (0.39) | GABRA5CTSACNR1ROCK2ROCK1 | |
| SCHEMBL25687225 | 0.93 | CFTR (0.35) | GABRA5CTSACNR1ROCK2ROCK1 | |
| SCHEMBL23958737 | 0.91 | POLB (0.35) | ROCK2ROCK1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |