Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.86 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247083 | 1.00 | KDM4E (0.86) | KDM4EPKMALDH1A1MAPK1VCAM1 | |
| SCHEMBL23148212 | 0.87 | KDM4E (0.67) | KDM4EPKMALDH1A1MAPK1VCAM1 | |
| SCHEMBL30008583 | 0.87 | KDM4E (0.67) | KDM4EPKMALDH1A1MAPK1VCAM1 | |
| SCHEMBL28508912 | 0.84 | KDM4E (0.62) | KDM4EPKMALDH1A1MAPK1VCAM1 | |
| SCHEMBL6564231 | 0.83 | KDM4E (0.61) | KDM4EPKMALDH1A1MAPK1LMNA | |
| SCHEMBL6563554 | 0.81 | KDM4E (0.59) | KDM4EPKMALDH1A1MAPK1LMNA | |
| SCHEMBL1873507 | 0.81 | PKM (1.00) | KDM4EPKMALDH1A1MAPK1LMNA | |
| SCHEMBL5813426 | 0.81 | ALDH1A1 (0.87) | KDM4EPKMALDH1A1MAPK1LMNA | |
| SCHEMBL3435820 | 0.80 | ALDH1A1 (0.65) | KDM4EPKMALDH1A1MAPK1KMT2A | |
| SCHEMBL27548843 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1MAPK1VCAM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105601-B | Benzenesulfonamide derivatives and related FERROSTATIN-1 analogs as cell death inhibitors | 维伯VZW公司 | 2022-11-18 | — | — | CN | disclosed |