Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | VCAM1 | P19320 | 9/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148212 | 1.00 | KDM4E (0.67) | KDM4EVCAM1LMNASMN1; SMN2PKM | |
| SCHEMBL30007934 | 0.87 | KDM4E (0.86) | KDM4EVCAM1LMNASMN1; SMN2PKM | |
| SCHEMBL21247083 | 0.87 | KDM4E (0.86) | KDM4EVCAM1LMNASMN1; SMN2PKM | |
| SCHEMBL28508912 | 0.87 | KDM4E (0.62) | KDM4EVCAM1LMNASMN1; SMN2PKM | |
| SCHEMBL21253089 | 0.83 | KDM4E (0.55) | KDM4EVCAM1LMNAMAPTALDH1A1 | |
| SCHEMBL15823836 | 0.80 | GAA (0.74) | KDM4ELMNASMN1; SMN2PKMGAA | |
| SCHEMBL17373973 | 0.80 | MEN1 (0.67) | KDM4ELMNASMN1; SMN2PKMGAA | |
| SCHEMBL7496013 | 0.80 | VCAM1 (0.79) | KDM4EVCAM1ALDH1A1MAPK1HTT | |
| SCHEMBL21253065 | 0.79 | WNK1 (0.53) | KDM4ELMNASMN1; SMN2PKMGAA | |
| SCHEMBL18556821 | 0.78 | VCAM1 (0.75) | KDM4EVCAM1PKMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105601-B | Benzenesulfonamide derivatives and related FERROSTATIN-1 analogs as cell death inhibitors | 维伯VZW公司 | 2022-11-18 | — | — | CN | disclosed |