Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CHKA | P35790 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13996861 | 0.98 | ALDH1A1 (0.56) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| Hydrochloric Acid SCHEMBL25439461 | 0.93 | CHKA (0.47) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| SCHEMBL12910774 | 0.91 | CHKA (0.49) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| SCHEMBL24038376 | 0.91 | CHKA (0.49) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| Hydrochloric Acid SCHEMBL25439458 | 0.90 | CHKA (0.47) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| Hydrochloric Acid SCHEMBL3761813 | 0.90 | ALDH1A1 (0.51) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| SCHEMBL3944502 | 0.88 | CHKA (0.52) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| Styrene SCHEMBL6464874 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| Bromide SCHEMBL5070701 | 0.86 | CHKA (0.53) | ALDH1A1KDM4ERAB9ACA1CA2 | |
| Hydrochloric Acid SCHEMBL1008024 | 0.86 | CA1 (0.48) | ALDH1A1KDM4ERAB9ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642778-B | Viologen compound, preparation method and application thereof | 淮阴师范学院 | 2022-10-04 | — | — | CN | disclosed |