Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24038376 | 0.98 | CHKA (0.49) | CHKAALDH1A1KDM4ERAB9ACA1 | |
| SCHEMBL12910774 | 0.98 | CHKA (0.49) | CHKAALDH1A1KDM4ERAB9ACA1 | |
| Hydrochloric Acid SCHEMBL25439458 | 0.96 | CHKA (0.47) | CHKAALDH1A1KDM4ERAB9ACA1 | |
| Hydrochloric Acid SCHEMBL30007947 | 0.93 | ALDH1A1 (0.58) | CHKAALDH1A1KDM4ERAB9ACA1 | |
| Hydrochloric Acid SCHEMBL27032936 | 0.92 | HDAC8 (0.53) | CHKAALDH1A1KDM4ERAB9ACA1 | |
| SCHEMBL13996861 | 0.91 | ALDH1A1 (0.56) | CHKAALDH1A1KDM4ERAB9ACA1 | |
| SCHEMBL12530148 | 0.90 | KDM4E (0.58) | CHKAALDH1A1KDM4ERAB9ACA1 | |
| SCHEMBL29989293 | 0.90 | HDAC8 (0.55) | CHKAALDH1A1KDM4ERAB9ACA1 | |
| SCHEMBL31598838 | 0.88 | ALDH1A1 (0.50) | CHKAALDH1A1CA1CA2BCHE | |
| SCHEMBL14002782 | 0.85 | LPL (0.41) | CHKAALDH1A1KDM4ERAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113025304-A | Electrochromic material and preparation method and application thereof | 中科院过程工程研究所南京绿色制造产业创新研究院 | 2021-06-25 | — | — | CN | claimed |
| US-20230178784-A1 | REDOX RELAY FLOW BATTERIES AND METHODS OF MAKING THE SAME | OHIO STATE INNOVATION FOUNDATION | 2023-06-08 | — | — | US | disclosed |
| CN-110642778-B | Viologen compound, preparation method and application thereof | 淮阴师范学院 | 2022-10-04 | — | — | CN | disclosed |
| CN-113025304-A | Electrochromic material and preparation method and application thereof | 中科院过程工程研究所南京绿色制造产业创新研究院 | 2021-06-25 | — | — | CN | disclosed |