Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290047 | 1.00 | GPR119 (0.36) | GPR119CYP2C9PIK3CD | |
| SCHEMBL757014 | 1.00 | GPR119 (0.36) | GPR119CYP2C9PIK3CD | |
| SCHEMBL3512362 | 1.00 | GPR119 (0.36) | GPR119CYP2C9PIK3CD | |
| SCHEMBL756593 | 0.89 | GPR119 (0.44) | GPR119PIK3CD | |
| SCHEMBL756592 | 0.89 | GPR119 (0.44) | GPR119PIK3CD | |
| SCHEMBL756660 | 0.89 | GPR119 (0.35) | GPR119CYP2C9PIK3CD | |
| SCHEMBL756178 | 0.88 | GPR119 (0.42) | GPR119CYP2C9 | |
| SCHEMBL298534 | 0.88 | GPR119 (0.42) | GPR119CYP2C9 | |
| SCHEMBL299176 | 0.88 | GPR119 (0.42) | GPR119CYP2C9 | |
| SCHEMBL288068 | 0.86 | GPR119 (0.47) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427450-A1 | GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |