Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290047 | 1.00 | GPR119 (0.36) | GPR119CYP2C9PIK3CD | |
| SCHEMBL300080 | 1.00 | GPR119 (0.36) | GPR119CYP2C9PIK3CD | |
| SCHEMBL3512362 | 1.00 | GPR119 (0.36) | GPR119CYP2C9PIK3CD | |
| SCHEMBL756593 | 0.89 | GPR119 (0.44) | GPR119PIK3CD | |
| SCHEMBL756592 | 0.89 | GPR119 (0.44) | GPR119PIK3CD | |
| SCHEMBL756660 | 0.89 | GPR119 (0.35) | GPR119CYP2C9PIK3CD | |
| SCHEMBL756178 | 0.88 | GPR119 (0.42) | GPR119CYP2C9 | |
| SCHEMBL298534 | 0.88 | GPR119 (0.42) | GPR119CYP2C9 | |
| SCHEMBL299176 | 0.88 | GPR119 (0.42) | GPR119CYP2C9 | |
| SCHEMBL288068 | 0.86 | GPR119 (0.47) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | claimed |
| US-20120052130-A1 | GPR 119 MODULATORS | PFIZER INC. | 2012-03-01 | — | — | US | disclosed |
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052130-A1 | GPR 119 MODULATORS | GPR119, GPR39, GPR65 | GPR119 1/4885CYP2C9 722/4885PIK3CD 2858/4885 |
| US-20100285145-A1 | GPR 119 MODULATORS | GPR119, GPR65, GPR39 | GPR119 1/4885CYP2C9 1406/4885PIK3CD 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.