SCHEMBL30008075

SCHEMBL30008075

CC(C)(C)c1ccc(Nc2ccc3c(c2)Oc2ccccc2O3)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 7/20 0.43
AHR P35869 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.38
KIF11 P52732 2/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
MTOR P42345 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KCNK9 Q9NPC2 1/20 0.36
ALDH1A1 P00352 1/20 0.35
AR P10275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23281215 0.84 AHR (0.52) AHRMEN1MAPTKMT2ATSHR
SCHEMBL22825075 0.82 ALDH1A1 (0.54) AHRMEN1MAPTKMT2ATSHR
SCHEMBL2389452 0.80 ALDH1A1 (0.56) AHRMEN1MAPTKMT2ATSHR
SCHEMBL25490552 0.80 AHR (0.48) AHRKIF11MEN1MAPTKMT2A
SCHEMBL18570306 0.77 ALDH1A1 (0.43) AHRABCG2MEN1MAPTKMT2A
SCHEMBL1009963 0.77 TRPV1 (0.62) TRPV1MEN1MAPTKMT2ATSHR
SCHEMBL22050052 0.76 MAPT (0.56) KIF11MEN1MAPTKMT2ATSHR
Diphenylamine SCHEMBL29287150 0.76 ALDH1A1 (0.62) TRPV1ABCG2MEN1MAPTKMT2A
SCHEMBL502030 0.76 ALDH1A1 (0.62) TRPV1ABCG2MEN1MAPTKMT2A
SCHEMBL2392625 0.75 TSHR (0.52) TRPV1ABCG2KIF11MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107840834-B Benzopyrene compound and application thereof 北京鼎材科技有限公司 2022-10-04 CN disclosed