SCHEMBL502030

SCHEMBL502030

CC(C)(C)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
HSD17B10 Q99714 5/20 0.62
ALOX12 P18054 4/20 0.62
L3MBTL1 Q9Y468 4/20 0.62
TSHR P16473 3/20 0.62
TDP1 Q9NUW8 3/20 0.62
ALOX15 P16050 2/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
MAPK1 P28482 1/20 0.62
PTGS2 P35354 1/20 0.62
HTR2B P41595 1/20 0.62
HPGD P15428 4/20 0.56
MAPT P10636 5/20 0.50
CYP3A4 P08684 5/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
HTT P42858 2/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL29287150 1.00 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL12367613 0.94 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL13133429 0.94 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL49741 0.90 TSHR (0.52) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL2392625 0.90 TSHR (0.52) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL20209149 0.89 ABCG2 (0.54) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL471147 0.89 NR3C2 (0.55) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL22080286 0.89 ABCG2 (0.54) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL605442 0.89 ABCG2 (0.54) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL15044317 0.87 ALDH1A1 (0.46) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 790 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078239-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION NYCO (FR) 2026-03-19 US claimed
EP-4514928-B1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A LUBRICANT COMPOSITION NYCO (FR) 2026-01-28 EP claimed
EP-4514928-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A LUBRICANT COMPOSITION NYCO (FR) 2025-03-05 EP claimed
US-20240360295-A1 STABILIZER COMBINATION FOR PREVENTING DEGRADATION OF SYNTHETIC POLYMERS BASF SE (DE) 2024-10-31 US claimed
CN-117821020-B Composite cooling medium composition and preparation method and application thereof 润威新材料科技(上海)有限公司 2024-08-16 CN claimed
EP-4007789-B1 CONTINUOUS PROCESS FOR THE POLYMERIZATION OR OLIGOMERIZATION OF DIPHENYLAMINES NYCO (FR) 2024-07-24 EP claimed
EP-4396256-A1 STABILIZER COMBINATION FOR PREVENTING DEGRADATION OF SYNTHETIC POLYMERS BASF SE (DE) 2024-07-10 EP claimed
CN-118308073-A Heat transfer dielectric fluid composition and application thereof 润威新材料科技(上海)有限公司 2024-07-09 CN claimed
CN-118239966-A Organic electroluminescent compound and application thereof 宁波卢米蓝新材料有限公司 2024-06-25 CN claimed
CN-114478412-B Amine compound, preparation method and application thereof, and antioxidant composition 中国石油化工股份有限公司 2024-06-11 CN claimed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US claimed
EP-0543778-A1 Compositions protected against oxydation and scorching, respectively polyetherpolyol and polyurethane CIBA-GEIGY AG (CH) 1993-05-26 EP claimed
EP-0346283-B1 LUBRICANT COMPOSITION CIBA-GEIGY AG (CH) 1992-07-29 EP claimed
EP-0480875-A1 Lubricating composition CIBA-GEIGY AG (CH) 1992-04-15 EP claimed
US-5091099-A Phosphite-free; containing aromatic amines and substituted phenols CIBA-GEIGY CORPORATION (US) 1992-02-25 US claimed
EP-0432089-A1 Lubricating oil compositions CIBA-GEIGY AG (CH) 1991-06-12 EP claimed
EP-0398215-A1 Lubricant compositions CIBA-GEIGY AG (CH) 1990-11-22 EP claimed
US-4963276-A MIXTURE OF AROMATIC AMINE AND ORGANOSULFUR COMPOUND CIBA-GEIGY CORPORATION (US) 1990-10-16 US claimed
EP-0346283-A2 Lubricant composition CIBA-GEIGY AG (CH) 1989-12-13 EP claimed
EP-0323403-A2 Lubricant composition CIBA-GEIGY AG (CH) 1989-07-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078239-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION GPX4, RAD50, POT1 ALDH1A1 1197/4885HSD17B10 947/4885ALOX12 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.