Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060208 | 1.00 | NPC1 (0.32) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6118106 | 0.85 | CYP19A1 (0.39) | — | |
| SCHEMBL6440830 | 0.76 | HTR6 (0.31) | — | |
| SCHEMBL13551397 | 0.70 | TP53 (0.33) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2963396 | 0.69 | CDC25B (0.38) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29060206 | 0.69 | — | — | |
| SCHEMBL30007549 | 0.69 | — | — | |
| SCHEMBL13409634 | 0.68 | NOS3 (0.39) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14678668 | 0.67 | CYP19A1 (0.37) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13473951 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025201477-A1 | SPIROCYCLIC GSDME INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) | 2025-10-02 | — | — | WO | disclosed |
| WO-2022237825-A1 | AZAARYL DERIVATIVE WITH EGFR INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-11-17 | — | — | WO | disclosed |