Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010172 | 0.90 | ALK (0.56) | ALKKDRKIT | |
| SCHEMBL30009705 | 0.89 | ALK (0.44) | ALK | |
| SCHEMBL30009523 | 0.87 | ALK (0.55) | ALKKDR | |
| SCHEMBL30009076 | 0.86 | ALK (0.50) | ALKKDRKIT | |
| SCHEMBL27087580 | 0.82 | ALK (0.64) | ALKKDRKIT | |
| SCHEMBL27087612 | 0.81 | ALK (0.52) | ALKKDRKIT | |
| SCHEMBL30009609 | 0.78 | ALK (0.61) | ALKKDRKIT | |
| SCHEMBL27087591 | 0.77 | ALK (0.65) | ALKKDRKIT | |
| SCHEMBL29940605 | 0.77 | ALK (0.38) | ALK | |
| SCHEMBL27087525 | 0.76 | ALK (0.41) | ALKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |