Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 11/20 | 0.44 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.40 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.40 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009083 | 0.89 | ALK (0.44) | ALK | |
| SCHEMBL30009875 | 0.86 | ALK (0.53) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL30009674 | 0.85 | ALK (0.46) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL30010172 | 0.84 | ALK (0.56) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL27087618 | 0.81 | ALK (0.64) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL29940605 | 0.81 | ALK (0.38) | ALKCA1CA2CA4CA6 | |
| SCHEMBL27087539 | 0.79 | ALK (0.48) | ALKCA1CA2CA4CA6 | |
| SCHEMBL27087612 | 0.78 | ALK (0.52) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL30009827 | 0.77 | ALK (0.45) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL30009523 | 0.76 | ALK (0.55) | ALKSRPK2SRPK1EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |