Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.32 |
| ▸ | FLT3 | P36888 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CFB | P00751 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20356899 | 0.80 | MAPK10 (0.46) | MAPK10RIPK1DRD2DRD3ITK | |
| SCHEMBL31737740 | 0.80 | MAPK10 (0.46) | MAPK10RIPK1DRD2DRD3ITK | |
| SCHEMBL30009067 | 0.78 | ALK (0.46) | ALKFLT3 | |
| SCHEMBL29940543 | 0.78 | CCNB2 (0.48) | DRD2DRD3 | |
| SCHEMBL30009089 | 0.67 | FLT3 (0.36) | ALKFLT3 | |
| SCHEMBL25183518 | 0.65 | MAPK10 (0.47) | MAPK10RIPK1ALKDRD2DRD3 | |
| SCHEMBL6849836 | 0.65 | GABRA1 (0.37) | — | |
| SCHEMBL5775576 | 0.65 | CYP11B1 (0.43) | — | |
| SCHEMBL9152103 | 0.65 | MAPT (0.50) | MAPK10RIPK1 | |
| SCHEMBL6739755 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |