SCHEMBL30009448

SCHEMBL30009448

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H](N)CCC(N)=O)C(C)C)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 5/20 0.50
▸ CTSD P07339 4/20 0.50
▸ CALCRL Q16602 3/20 0.46
▸ CTSE P14091 1/20 0.44
▸ NPY2R P49146 5/20 0.44
▸ NPY4R P50391 5/20 0.44
▸ NPY5R Q15761 5/20 0.44
▸ NPY1R P25929 4/20 0.44
▸ RAMP3 O60896 3/20 0.44
▸ CALCR P30988 3/20 0.44
▸ RAMP1 O60894 1/20 0.43
▸ FCGRT P55899 2/20 0.43
▸ KEAP1 Q14145 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30978825 0.88 BACE1 (0.50) BACE1CTSDNPY2RNPY4RNPY5R
SCHEMBL31031606 0.87 KEAP1 (0.43) BACE1CTSDCALCRLRAMP1KEAP1
SCHEMBL30079002 0.86 CALCRL (0.47) BACE1CTSDCALCRLCTSERAMP1
SCHEMBL30401916 0.85 NPY2R (0.52) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL9058997 0.85 RAMP3 (0.56) CALCRLNPY2RNPY4RNPY5RNPY1R
SCHEMBL9058995 0.85 RAMP3 (0.56) CALCRLNPY2RNPY4RNPY5RNPY1R
SCHEMBL31151696 0.84 F2 (0.46) RAMP3CALCRKEAP1
SCHEMBL30930139 0.84 CALCR (0.56) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30401788 0.84 NPY2R (0.52) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30608590 0.84 CTSD (0.44) BACE1CTSDCALCRLNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240109942-A1 CHOLECYSTOKININ (CCK) SECRETION-PROMOTING PEPTIDE TARGETING CALCIUM-SENSING RECEPTOR, AND PREPARATION METHOD AND USE THEREOF UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY (CN) 2024-04-04 — — US claimed
WO-2024001484-A1 CCK SECRETION-PROMOTING PEPTIDE TARGETING CALCIUM SENSING RECEPTOR AND METHOD FOR PREPARING SAME AND USE THEREOF 上海理工大学 2024-01-04 — — WO claimed
US-20240109942-A1 CHOLECYSTOKININ (CCK) SECRETION-PROMOTING PEPTIDE TARGETING CALCIUM-SENSING RECEPTOR, AND PREPARATION METHOD AND USE THEREOF UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY (CN) 2024-04-04 — — US disclosed
US-20240109942-A1 CHOLECYSTOKININ (CCK) SECRETION-PROMOTING PEPTIDE TARGETING CALCIUM-SENSING RECEPTOR, AND PREPARATION METHOD AND USE THEREOF UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY (CN) 2024-04-04 — — US disclosed
CN-115353551-B Oat-derived GLP-1 secretion-promoting oligopeptide and preparation method and application thereof 上海理工大学 2024-01-26 — — CN disclosed
WO-2024001484-A1 CCK SECRETION-PROMOTING PEPTIDE TARGETING CALCIUM SENSING RECEPTOR AND METHOD FOR PREPARING SAME AND USE THEREOF 上海理工大学 2024-01-04 — — WO disclosed
CN-115353553-B CCK secretion-promoting peptide targeting calcium sensitive receptor and preparation method and application thereof 上海理工大学 2023-06-02 — — CN disclosed
CN-115353553-B CCK secretion-promoting peptide targeting calcium sensitive receptor and preparation method and application thereof 上海理工大学 2023-06-02 — — CN disclosed
CN-115353553-A CCK secretion promoting peptide targeting calcium sensitive receptor and preparation method and application thereof 上海理工大学 2022-11-18 — — CN disclosed
CN-115353553-A CCK secretion promoting peptide targeting calcium sensitive receptor and preparation method and application thereof 上海理工大学 2022-11-18 — — CN disclosed
CN-115353551-A Oat-derived GLP-1 secretion promoting oligopeptide and preparation method and application thereof 上海理工大学 2022-11-18 — — CN disclosed
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