Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20934574 | 0.88 | CES2 (0.54) | CES2CES1PARP1KDM2BMEN1 | |
| SCHEMBL20934473 | 0.88 | CES2 (0.54) | CES2CES1PARP1KDM2BMEN1 | |
| SCHEMBL31636008 | 0.83 | CES2 (0.65) | CES2CES1PARP1KDM2BMEN1 | |
| SCHEMBL7309424 | 0.83 | CES2 (0.65) | CES2CES1PARP1KDM2BMEN1 | |
| SCHEMBL18360283 | 0.81 | KDM2B (0.62) | CES2CES1PARP1KDM2BMEN1 | |
| SCHEMBL12858209 | 0.81 | ALDH1A1 (0.57) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL5210032 | 0.79 | MGLL (0.62) | CES2CES1PARP1KDM2BMEN1 | |
| SCHEMBL2992324 | 0.79 | CES2 (0.54) | CES2CES1PARP1KDM2BMEN1 | |
| SCHEMBL2992325 | 0.79 | CES2 (0.54) | CES2CES1PARP1KDM2BMEN1 | |
| SCHEMBL30771226 | 0.79 | MGLL (0.62) | CES2CES1PARP1KDM2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | disclosed |