Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.46 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.46 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.46 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009076 | 0.90 | ALK (0.50) | ALKKDRKIT | |
| SCHEMBL30010452 | 0.87 | ALK (0.59) | ALKSRPK2SRPK1EML4KDR | |
| SCHEMBL30009705 | 0.85 | ALK (0.44) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL30009609 | 0.84 | ALK (0.61) | ALKSRPK2SRPK1EML4KDR | |
| SCHEMBL27087512 | 0.82 | ALK (0.66) | ALKSRPK2SRPK1EML4KDR | |
| SCHEMBL30009083 | 0.76 | ALK (0.44) | ALKKDRKIT | |
| SCHEMBL27087552 | 0.75 | ALK (0.72) | ALKSRPK2SRPK1EML4KDR | |
| SCHEMBL30010134 | 0.74 | ALK (0.42) | ALKSRPK2SRPK1EML4KDR | |
| SCHEMBL27087575 | 0.73 | ALK (0.72) | ALKSRPK2SRPK1EML4KDR | |
| SCHEMBL27087592 | 0.73 | ALK (0.67) | ALKSRPK2SRPK1EML4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |