Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25655884 | 1.00 | KMT2A (0.51) | KMT2AALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL15851174 | 0.82 | ALDH1A1 (0.41) | KMT2AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL12279379 | 0.80 | ALDH1A1 (0.40) | KMT2AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL18133619 | 0.80 | ALDH1A1 (0.40) | KMT2AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL13435569 | 0.80 | CYP1A1 (0.62) | KMT2AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL13561968 | 0.80 | ALDH1A1 (0.41) | KMT2AALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL4420514 | 0.79 | ALDH1A1 (0.45) | KMT2AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL14231869 | 0.78 | CYP1A1 (0.51) | KMT2AALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL17083900 | 0.77 | HPGD (0.59) | KMT2AALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL11643109 | 0.74 | MAOB (0.54) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111067889-B | Application of 2-methyl naphtho [1,2-b ] furan compound in preparation of medicine related to diabetic nephropathy | 徐州医科大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-111067889-B | Application of 2-methyl naphtho [1,2-b ] furan compound in preparation of medicine related to diabetic nephropathy | 徐州医科大学 | 2022-11-18 | — | — | CN | disclosed |