Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23392966 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL23392645 | 0.82 | MEN1 (0.42) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL30013487 | 0.82 | MEN1 (0.42) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL23202287 | 0.78 | PNP (0.52) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL5173890 | 0.77 | TRAP1 (0.53) | ALDH1A1MEN1KMT2AMAPTATM | |
| SCHEMBL26924018 | 0.77 | LMNA (0.38) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL23202297 | 0.74 | MEN1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2ADORA2B | |
| SCHEMBL30013359 | 0.74 | MEN1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2ADORA2B | |
| SCHEMBL30012724 | 0.73 | SMN1; SMN2 (0.39) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23392754 | 0.73 | SMN1; SMN2 (0.39) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427063-A | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |