Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121187 | 0.84 | DPP4 (0.44) | NAMPTROCK2ROCK1FAP | |
| SCHEMBL30013223 | 0.83 | ABHD6 (0.38) | NAMPTABHD6 | |
| SCHEMBL31121184 | 0.82 | FAP (0.39) | NAMPTFAP | |
| SCHEMBL23745206 | 0.77 | ADAMTS5 (0.53) | — | |
| SCHEMBL29835210 | 0.77 | ADAMTS5 (0.53) | — | |
| SCHEMBL23745230 | 0.76 | ADAMTS5 (0.37) | — | |
| SCHEMBL31121176 | 0.76 | DPP8 (0.40) | NAMPTMEN1 | |
| SCHEMBL23745212 | 0.71 | ADAMTS5 (0.52) | — | |
| SCHEMBL30013191 | 0.70 | ADAMTS5 (0.34) | — | |
| SCHEMBL30013203 | 0.67 | DPP7 (0.41) | NAMPTFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100005-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2022-12-14 | — | — | EP | disclosed |