SCHEMBL3001278

SCHEMBL3001278

CC1CC(C2(C)CCC3CCC2C3)C2CCCC12

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 3/20 0.39
GRIN2B Q13224 3/20 0.39
NR1I3 Q14994 2/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
LMNA P02545 2/20 0.35
GPBAR1 Q8TDU6 2/20 0.35
SHBG P04278 1/20 0.35
SERPINA6 P08185 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2999923 0.85 GRIN1 (0.32) GRIN1GRIN2B
SCHEMBL2992356 0.78 NR1I3 (0.34) NR1I3CDK5CDK5R1LMNAGPBAR1
SCHEMBL2998420 0.75 LMNA (0.33) GRIN1GRIN2BLMNAGPBAR1SHBG
SCHEMBL3003235 0.73 CYP19A1 (0.31) GRIN1GRIN2B
SCHEMBL2997217 0.70 LMNA (0.39) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL2999913 0.69 LMNA (0.33) NR1I3CDK5CDK5R1LMNAGPBAR1
SCHEMBL2998617 0.69 LMNA (0.33) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL2989167 0.66
SCHEMBL2988087 0.64
SCHEMBL2992636 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US claimed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US disclosed
EP-0508292-A1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-14 EP disclosed