SCHEMBL2992356

SCHEMBL2992356

CC1C2CCCC2CC1C1(C)CCC2CCC1C2

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1I3 Q14994 2/20 0.34
CDK5 Q00535 1/20 0.34
CDK5R1 Q15078 1/20 0.34
GPBAR1 Q8TDU6 5/20 0.33
LMNA P02545 3/20 0.33
SHBG P04278 3/20 0.33
SERPINA6 P08185 3/20 0.33
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B3 P37058 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2988087 0.86
SCHEMBL3001278 0.78 GRIN1 (0.39) NR1I3CDK5CDK5R1GPBAR1LMNA
SCHEMBL2995587 0.78 CYP19A1 (0.37)
SCHEMBL2998617 0.76 LMNA (0.33) GPBAR1LMNASHBGSERPINA6CYP3A4
SCHEMBL2997217 0.72 LMNA (0.39) GPBAR1LMNASHBGSERPINA6CYP3A4
SCHEMBL2998420 0.70 LMNA (0.33) GPBAR1LMNASHBGSERPINA6CYP3A4
SCHEMBL2993101 0.69
SCHEMBL2991580 0.67 CDK5 (0.33) NR1I3CDK5CDK5R1SHBGHSD17B10
SCHEMBL2999913 0.67 LMNA (0.33) NR1I3CDK5CDK5R1GPBAR1LMNA
SCHEMBL2991565 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US claimed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US disclosed
EP-0508292-A1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-14 EP disclosed