SCHEMBL2997217

SCHEMBL2997217

CC1(C2CCC3CCC2C3)CCC2CCC1C2

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
GPBAR1 Q8TDU6 2/20 0.39
SHBG P04278 1/20 0.39
SERPINA6 P08185 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2998617 0.82 LMNA (0.33) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL2998420 0.82 LMNA (0.33) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL2996486 0.76 CYP19A1 (0.33)
SCHEMBL2999913 0.75 LMNA (0.33) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL11880853 0.74 CDK5 (0.42) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL11880232 0.74 CDK5 (0.42) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL2992356 0.72 NR1I3 (0.34) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL19253185 0.70 LMNA (0.55) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL3001278 0.70 GRIN1 (0.39) LMNAGPBAR1SHBGSERPINA6CYP1A2
SCHEMBL2991580 0.68 CDK5 (0.33) SHBGHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US claimed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US disclosed
EP-0508292-A1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-14 EP disclosed