Epigalocatechin Gallate

Epigalocatechin Gallate

SCHEMBL30014282

O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 10/20 1.00
BACE1 P56817 5/20 1.00
MMP2 P08253 5/20 1.00
MMP7 P09237 5/20 1.00
MMP14 P50281 5/20 1.00
BCL2 P10415 4/20 1.00
PSMB5 P28074 4/20 1.00
SNCA P37840 4/20 1.00
PGD P52209 4/20 1.00
MET P08581 3/20 1.00
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 3/20 1.00
MAPT P10636 3/20 1.00
RECQL P46063 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
PKM P14618 3/20 1.00
PKMYT1 Q99640 2/20 1.00
PGAM1 P18669 2/20 1.00
SIRT6 Q8N6T7 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epigalocatechin Gallate SCHEMBL29389587 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Gallocatechin Gallate SCHEMBL30977114 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL30909383 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL10198783 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL14423426 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL35258 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Gallocatechin Gallate SCHEMBL49461 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL13624466 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL8426376 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL29410018 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380633-A2 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF Rayzebio, Inc. (US) 2024-06-12 EP claimed
CN-118103078-A Stabilized compositions of radionuclides and uses thereof 瑞择生物公司 2024-05-28 CN claimed
WO-2023191839-A9 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. (US) 2023-11-09 WO claimed
WO-2023191839-A2 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. (US) 2023-10-05 WO claimed
EP-4719497-A1 METHODS FOR TREATING SSTR POSITIVE CANCER Rayzebio, Inc. (US) 2026-04-08 EP disclosed
US-12514939-B2 Stable radiopharmaceutical compositions and uses thereof ALPHA-9 ONCOLOGY, INC. (CA) 2026-01-06 US disclosed
EP-4194548-B1 GENERATION OF HUMAN PLURIPOTENT STEM CELL DERIVED FUNCTIONAL BETA CELLS SHOWING A GLUCOSE-DEPENDENT MITOCHONDRIAL RESPIRATION AND TWO-PHASE INSULIN SECRETION RESPONSE JANSSEN BIOTECH INC (US) 2025-10-22 EP disclosed
EP-4618965-A1 NOVEL OPHTHALMIC FORMULATION Fertis India Pvt. Ltd. (IN) 2025-09-24 EP disclosed
US-20250255993-A1 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND USES THEREOF ALPHA-9 ONCOLOGY INC. (CA) 2025-08-14 US disclosed
WO-2024248823-A1 METHODS FOR TREATING SSTR POSITIVE CANCER RAYZEBIO, INC. (US) 2024-12-05 WO disclosed
WO-2024249352-A1 METHODS FOR TREATING SSTR POSITIVE CANCER RAYZEBIO, INC. (US) 2024-12-05 WO disclosed
CN-118831183-A Stabilized compositions of radionuclides and uses thereof 瑞择生物公司 2024-10-25 CN disclosed
WO-2024158981-A1 COMPOSITIONS AND METHODS FOR REDUCING THE RATE OF TYPE 1 DIABETES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-08-02 WO disclosed
EP-4380633-A2 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF Rayzebio, Inc. (US) 2024-06-12 EP disclosed
CN-118103078-A Stabilized compositions of radionuclides and uses thereof 瑞择生物公司 2024-05-28 CN disclosed
WO-2023191839-A9 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. (US) 2023-11-09 WO disclosed
WO-2023191839-A2 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. (US) 2023-10-05 WO disclosed
EP-3472303-B1 GENERATION OF HUMAN PLURIPOTENT STEM CELL DERIVED FUNCTIONAL BETA CELLS SHOWING A GLUCOSE-DEPENDENT MITOCHONDRIAL RESPIRATION AND TWO-PHASE INSULIN SECRETION RESPONSE JANSSEN BIOTECH INC (US) 2022-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250255993-A1 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND USES THEREOF RCN1, RABL6, QPCT DYRK1A 3164/4885BACE1 2193/4885MMP2 3886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.