Epigalocatechin Gallate

Epigalocatechin Gallate

SCHEMBL35258

O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 10/20 1.00
BACE1 P56817 5/20 1.00
MMP2 P08253 5/20 1.00
MMP7 P09237 5/20 1.00
MMP14 P50281 5/20 1.00
BCL2 P10415 4/20 1.00
PSMB5 P28074 4/20 1.00
SNCA P37840 4/20 1.00
PGD P52209 4/20 1.00
MET P08581 3/20 1.00
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 3/20 1.00
MAPT P10636 3/20 1.00
RECQL P46063 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
PKM P14618 3/20 1.00
PKMYT1 Q99640 2/20 1.00
PGAM1 P18669 2/20 1.00
SIRT6 Q8N6T7 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epigalocatechin Gallate SCHEMBL29389587 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Gallocatechin Gallate SCHEMBL30977114 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL30014282 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL30909383 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL10198783 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL14423426 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Gallocatechin Gallate SCHEMBL49461 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL13624466 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL8426376 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL29410018 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 28947 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121445868-B Near infrared light-excitable composite nano sheet and preparation method and application thereof JILIN UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122075796-A Bionic nerve conduit and preparation method and application thereof 2026-05-26 CN claimed
CN-122074603-A Compounding method for improving solubility of hesperidin in concentrated orange juice 2026-05-26 CN claimed
CN-121337987-B Injectable hydrogel for photothermal adjuvant therapy of periodontitis and preparation method thereof JILIN UNIVERSITY (CN) 2026-05-26 CN claimed
US-12636311-B2 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation GALLEON LABS LLC (US) 2026-05-26 US claimed
CN-122075620-A Mulberry leaf and wolfberry fruit composition, oral preparation and application thereof 2026-05-26 CN claimed
CN-122075328-A Dentifrice with whitening, tooth stain removing and anti-inflammatory effects and preparation method thereof 2026-05-26 CN claimed
CN-122075325-A Skin care composition, skin care product and application thereof 2026-05-26 CN claimed
US-12637498-B2 PDLIM2 as a biomarker for cancer and as an anti-cancer treatment target University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2026-05-26 US claimed
CN-121059563-B Liquid phase stable high-content coenzyme Q10Composite microcapsule and preparation method and application thereof Wang Shuhe Biomedical (Wuhan) Co.,Ltd. (CN) 2026-05-26 CN claimed
EP-0443090-A2 Agent for preventing infection with methicillin-resistant staphylococcus MITSUI NORIN CO., LTD. (JP) 1991-08-28 EP claimed
EP-0423419-A1 Inhibitive agent against activity of alpha-amylase MITSUI NORIN CO., LTD. (JP) 1991-04-24 EP claimed
EP-0417385-A2 Preventive and curative medicament against infection with influenza virus, containing tea or tea polyphenols MITSUI NORIN CO., LTD. (JP) 1991-03-20 EP claimed
EP-0415126-A1 Anti-dental plaque agents MITSUI NORIN CO., LTD. (JP) 1991-03-06 EP claimed
EP-0397914-A1 Antitoxins for bacterial exotoxins MITSUI NORIN CO., LTD. (JP) 1990-11-22 EP claimed
EP-0374888-A2 Sulfated tannins and theirs salts YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1990-06-27 EP claimed
US-4613672-A SOLVENT EXTRACTION MITSU NORIN CO., LTD. (JP) 1986-09-23 US claimed
US-4585738-A FOOD PROCESSING KRAFT, INC. (US) 1986-04-29 US claimed
US-4517175-A FLAVANOL DERIVATIVES AND PROTEINS KAO CORPORATION (JP) 1985-05-14 US claimed
US-4248789-A MIXING CAFFEINE SOLUTION WITH TANNIC SOLUTION EXTRACTED FROM TEA DIRECTOR OF NATIONAL RESEARCH INSTITUTE OF TEA (JP) 1981-02-03 US claimed