Gallocatechin Gallate

Gallocatechin Gallate

SCHEMBL49461

O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 10/20 1.00
BACE1 P56817 5/20 1.00
MMP2 P08253 5/20 1.00
MMP7 P09237 5/20 1.00
MMP14 P50281 5/20 1.00
BCL2 P10415 4/20 1.00
PSMB5 P28074 4/20 1.00
SNCA P37840 4/20 1.00
PGD P52209 4/20 1.00
MET P08581 3/20 1.00
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 3/20 1.00
MAPT P10636 3/20 1.00
RECQL P46063 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
PKM P14618 3/20 1.00
PKMYT1 Q99640 2/20 1.00
PGAM1 P18669 2/20 1.00
SIRT6 Q8N6T7 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epigalocatechin Gallate SCHEMBL29389587 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Gallocatechin Gallate SCHEMBL30977114 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL30014282 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL30909383 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL10198783 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL14423426 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL35258 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL13624466 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL8426376 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14
Epigalocatechin Gallate SCHEMBL29410018 1.00 DYRK1A (1.00) DYRK1ABACE1MMP2MMP7MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2966 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031766-A Cu2+Chelating EGCG nanoparticle functionalized composite bone repair hydrogel material and preparation method thereof 青岛大学附属医院 2026-05-15 CN claimed
EP-4739275-A1 VITELLARIA PARADOXA EXTRACT COMPOSITION Bunge Loders Croklaan B.V. (NL) 2026-05-13 EP claimed
EP-4606388-A9 METAL-POLYPHENOL COMPLEX PARTICLE, DRUG-LIPID PARTICLE, METHOD FOR PREPARING SAME, AND USE THEREOF Hunan Lonstar Biotech Co., Ltd. (CN) 2026-02-25 EP claimed
US-20260048142-A1 METAL-CHELATED POLYPHENOL COMPLEX NANOPARTICLE, DRUG-LIPID PARTICLE, PREPARATION METHODS FOR THE SAME, AND USES THEREOF HUNAN LONSTAR BIOTECH CO LTD (CN) 2026-02-19 US claimed
US-20260028675-A1 PRECISION MEDICINE FOR PAIN: DIAGNOSTIC BIOMARKERS, PHARMACOGENOMICS, AND REPURPOSED DRUGS UNIV INDIANA RES & TECH CORP (US) 2026-01-29 US claimed
EP-4664553-A1 NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE SLURRY, NEGATIVE ELECTRODE, AND SECONDARY BATTERY LG Energy Solution, Ltd. (KR) 2025-12-17 EP claimed
EP-4647070-A2 A PHARMACEUTICAL COMPOSITION FOR REDUCING LOCAL FAT AND USES THEREOF Caliway Biopharmaceuticals Co. Ltd. (TW) 2025-11-12 EP claimed
WO-2025227040-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF INTRAEPITHELIAL DYSPLASIA AND NEOPLASIA AMPLEXD THERAPEUTICS, INC. (US) 2025-10-30 WO claimed
EP-4606388-A1 METAL-POLYPHENOL COMPLEX PARTICLE, DRUG-LIPID PARTICLE, METHOD FOR PREPARING SAME, AND USE THEREOF Hunan Lonstar Biotech Co., Ltd. (CN) 2025-08-27 EP claimed
US-12364728-B2 Composition for reducing body fat comprising green tea extract containing gallocatechin gallate as an active ingredient and manufacturing method thereof AMOREPACIFIC CORPORATION (KR) 2025-07-22 US claimed
EP-1207862-A2 ARTHRITIS TREATMENT THE UNIVERSITY OF SHEFFIELD (GB) 2002-05-29 EP claimed
WO-2002039822-A2 PACKAGED BEVERAGES KAO CORPORATION (JP) 2002-05-23 WO claimed
US-20020054924-A1 Novel compositions derived from cranberry and grapefruit and therapeutic uses therefor LEAHY MARGARET M (US) 2002-05-09 US claimed
WO-2002033404-A2 INTEGRATED WINE QUALITY SENSOR TRAUNER KENNETH B (US) 2002-04-25 WO claimed
US-20020034576-A1 Carbonated beverage for strengthening acid resistancy of teeth (with the taste of cream soda) BURGESS JAMES MICHEAL (US) 2002-03-21 US claimed
WO-2001080870-A2 COMPOSITIONS DERIVED FROM CRANBERRY AND GRAPEFRUIT AND THERAPEUTIC USES THEREFOR OCEAN SPRAY CRANBERRIES, INC. (US) 2001-11-01 WO claimed
WO-2001049307-A1 CATECHINS AND GREEN TEA EXTRACT FOR THE TREATMENT OF AMYLOIDOSIS IN ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES PROTEOTECH, INC. (US) 2001-07-12 WO claimed
WO-2000074662-A2 ARTHRITIS TREATMENT UNIVERSITY OF SHEFFIELD (GB) 2000-12-14 WO claimed
US-5750563-A MIXING A CATECHIN, A FLAVONE, OR A TANNIN INTO EMULSIFIED MIXTURE OF KOJIC ACID, NONIONIC SURFACTANT, AND ULTRAVIOLET LIGHT ABSORBER; STABILIZATION, DISCOLORATION INHIBITION SANSHO SEIYAKU CO., LTD. (JP) 1998-05-12 US claimed
US-5204089-A Using a tea leaf polyphenol e.g., acatchin gallate, theaflavin or a theaflavin gallate; streptococcus glucosyltransferase inhibitor MITSUI NORIN CO., LTD. (JP) 1993-04-20 US claimed