Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 10/20 | 1.00 |
| ▸ | BACE1 | P56817 | 5/20 | 1.00 |
| ▸ | MMP2 | P08253 | 5/20 | 1.00 |
| ▸ | MMP7 | P09237 | 5/20 | 1.00 |
| ▸ | MMP14 | P50281 | 5/20 | 1.00 |
| ▸ | BCL2 | P10415 | 4/20 | 1.00 |
| ▸ | PSMB5 | P28074 | 4/20 | 1.00 |
| ▸ | SNCA | P37840 | 4/20 | 1.00 |
| ▸ | PGD | P52209 | 4/20 | 1.00 |
| ▸ | MET | P08581 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 1.00 |
| ▸ | PGAM1 | P18669 | 2/20 | 1.00 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epigalocatechin Gallate SCHEMBL29389587 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Gallocatechin Gallate SCHEMBL30977114 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL30014282 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL30909383 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL10198783 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL14423426 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL35258 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Gallocatechin Gallate SCHEMBL49461 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL8426376 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL29410018 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744820-B2 | Inhibitors of microbially induced amyloid | AXIAL THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20210252097-A1 | POLYPHARMACEUTICAL DRUG COMPOSITIONS AND RELATED METHODS | AVETA BIOMICS, INC. (US) | 2021-08-19 | — | — | US | disclosed |
| EP-3560587-A1 | METHOD FOR SYNTHESIS OF A METAL ORGANIC FRAMEWORK COMPOSITE | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2019-10-30 | — | — | EP | disclosed |
| US-9795597-B2 | Cyclopropylamines as LSD1 inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-10-24 | — | — | US | disclosed |
| US-9408407-B2 | Compounds, compositions, and methods for reducing or eliminating bitter taste | CHROMOCELL CORPORATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-20160220547-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-08-04 | — | — | US | disclosed |
| US-20150313906-A1 | COMBINATION | GLAXOSMITHKLINE LLC | 2015-11-05 | — | — | US | disclosed |
| US-20150313906-A1 | COMBINATION | GLAXOSMITHKLINE LLC | 2015-11-05 | — | — | US | disclosed |
| US-20150306099-A1 | COMBINATION | GLAXOSMITHKLINE LLC | 2015-10-29 | — | — | US | disclosed |
| US-20150306099-A1 | COMBINATION | GLAXOSMITHKLINE LLC | 2015-10-29 | — | — | US | disclosed |
| US-20150237900-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORP (US) | 2015-08-27 | — | — | US | disclosed |
| US-8865779-B2 | Compounds, compositions, and methods for reducing or eliminating bitter taste | CHROMOCELL CORPORATION (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130287918-A1 | MICROBICIDAL COMPOSITION | DUPONT NUTRITION DIOSCIENCES APS (DK) | 2013-10-31 | — | — | US | disclosed |
| US-20130287918-A1 | MICROBICIDAL COMPOSITION | DUPONT NUTRITION DIOSCIENCES APS (DK) | 2013-10-31 | — | — | US | disclosed |
| US-20130096209-A1 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2013-04-18 | — | — | US | disclosed |
| EP-2119712-A1 | NOVEL METHYLATED CATECHIN AND COMPOSITION CONTAINING THE SAME | Incorporated Administrative Agency National Agriculture and Food Research Organization (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220547-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | KDM1B, KDM1A, KDM3B | DYRK1A 1348/4885BACE1 1181/4885MMP2 3081/4885 |
| US-20210252097-A1 | POLYPHARMACEUTICAL DRUG COMPOSITIONS AND RELATED METHODS | PCBP1, CYP3A5, ABCB1 | DYRK1A 2796/4885BACE1 1152/4885MMP2 4763/4885 |
| US-20150306099-A1 | COMBINATION | VHL, CA5A, HRAS | DYRK1A 2340/4885BACE1 3057/4885MMP2 4608/4885 |
| US-11744820-B2 | Inhibitors of microbially induced amyloid | APP, PSEN1, BACE1 | DYRK1A 4091/4885BACE1 3/4885MMP2 1057/4885 |
| US-20150237900-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | TAS2R5, TAS2R20, TAS2R10 | DYRK1A 3989/4885BACE1 4010/4885MMP2 4785/4885 |
| US-20150313906-A1 | COMBINATION | EZH2, BMI1, DOT1L | DYRK1A 583/4885BACE1 2450/4885MMP2 4137/4885 |
| US-20130096209-A1 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste | TAS2R5, TAS2R20, TAS2R10 | DYRK1A 3989/4885BACE1 4010/4885MMP2 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.