Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607137 | 0.84 | HSD17B10 (0.45) | HSD17B10CA2CA4TPMTKDM4E | |
| SCHEMBL442742 | 0.84 | ALDH1A1 (0.44) | HSD17B10CA2CA4TPMTALDH1A1 | |
| SCHEMBL23409566 | 0.78 | KMT2A (0.45) | HSD17B10CA2TPMTALDH1A1KDM4E | |
| SCHEMBL29970457 | 0.78 | KMT2A (0.45) | HSD17B10CA2TPMTALDH1A1KDM4E | |
| SCHEMBL3521150 | 0.78 | HSD17B10 (0.50) | HSD17B10CA2CA4TPMTALDH1A1 | |
| SCHEMBL30017049 | 0.77 | KDM4E (0.43) | HSD17B10CA2CA4TPMTALDH1A1 | |
| SCHEMBL19607300 | 0.77 | KDM4E (0.43) | HSD17B10CA2CA4TPMTALDH1A1 | |
| SCHEMBL931631 | 0.77 | POLB (0.44) | HSD17B10CA2CA4TPMTALDH1A1 | |
| SCHEMBL20523636 | 0.75 | GAA (0.41) | HSD17B10CA2CA4TPMTALDH1A1 | |
| SCHEMBL21823580 | 0.75 | TPMT (0.55) | HSD17B10CA2CA4TPMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |