Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607137 | 0.88 | HSD17B10 (0.45) | HSD17B10CA2CA4ALOX15ALOX12 | |
| SCHEMBL301662 | 0.83 | HSD17B10 (0.59) | HSD17B10CA2CA4ALOX15ALOX12 | |
| SCHEMBL1530384 | 0.82 | CA2 (0.52) | HSD17B10CA2CA4ALOX15ALOX12 | |
| SCHEMBL19607300 | 0.80 | KDM4E (0.43) | HSD17B10CA2CA4ALOX15ALOX12 | |
| SCHEMBL30017049 | 0.80 | KDM4E (0.43) | HSD17B10CA2CA4ALOX15ALOX12 | |
| SCHEMBL24252805 | 0.78 | HSD17B10 (0.35) | HSD17B10CA2CA4ALOX15ALOX12 | |
| SCHEMBL30015664 | 0.78 | HSD17B10 (0.35) | HSD17B10CA2CA4ALOX15ALOX12 | |
| SCHEMBL482635 | 0.78 | CA2 (0.43) | HSD17B10CA2CA4TPMTMAPT | |
| SCHEMBL12678876 | 0.75 | PTGS2 (0.40) | HSD17B10CA2CA4ALOX15TPMT | |
| SCHEMBL11216824 | 0.74 | HSD17B10 (0.52) | HSD17B10CA2CA4ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307372-B1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2012-04-25 | — | — | EP | disclosed |