Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30017722 | 0.92 | GRIN1 (0.47) | GRIN1GRIN2BEPHX2PPARGQPCT | |
| SCHEMBL30018106 | 0.91 | GRIN1 (0.39) | GRIN1GRIN2BSHMT2RAB9AEPHX2 | |
| SCHEMBL30018748 | 0.86 | GRIN1 (0.44) | GRIN1GRIN2BSHMT2RAB9AKMO | |
| SCHEMBL30017921 | 0.86 | HTR2A (0.40) | GRIN1GRIN2BEPHX2PPARGQPCT | |
| SCHEMBL30017931 | 0.85 | GRIN1 (0.43) | GRIN1GRIN2BEPHX2PPARGEGFR | |
| SCHEMBL30017725 | 0.84 | SHMT2 (0.41) | GRIN1GRIN2BSHMT2RAB9AEPHX2 | |
| SCHEMBL30018361 | 0.82 | QPCT (0.47) | GRIN1GRIN2BSHMT2RAB9AKMO | |
| SCHEMBL30018866 | 0.80 | SHMT2 (0.41) | GRIN1GRIN2BSHMT2RAB9AEPHX2 | |
| SCHEMBL24784619 | 0.79 | P2RX7 (0.38) | GRIN1GRIN2BEPHX2PPARGP2RX7 | |
| SCHEMBL30103035 | 0.79 | P2RX7 (0.38) | GRIN1GRIN2BEPHX2PPARGP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |