Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784619 | 1.00 | P2RX7 (0.38) | P2RX7ALKBH1KDM4ELDHAROCK2 | |
| SCHEMBL24785460 | 0.93 | ALKBH1 (0.41) | P2RX7ALKBH1LDHAROCK2GRK6 | |
| SCHEMBL30103033 | 0.93 | ALKBH1 (0.41) | P2RX7ALKBH1LDHAROCK2GRK6 | |
| SCHEMBL30103053 | 0.92 | P2RX7 (0.39) | P2RX7ALKBH1ROCK2GRK6KMT2A | |
| SCHEMBL24784614 | 0.92 | P2RX7 (0.39) | P2RX7ALKBH1ROCK2GRK6KMT2A | |
| SCHEMBL24784641 | 0.88 | MDM2 (0.36) | KDM4EKMT2A | |
| SCHEMBL30103123 | 0.88 | MDM2 (0.36) | KDM4EKMT2A | |
| SCHEMBL24784545 | 0.87 | NPBWR1 (0.41) | KDM4EKMT2APTPN1 | |
| SCHEMBL30103058 | 0.87 | NPBWR1 (0.41) | KDM4EKMT2APTPN1 | |
| SCHEMBL24784635 | 0.87 | ALKBH1 (0.36) | ALKBH1LDHAROCK2GRK6PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |