Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535205 | 0.76 | KDM4E (0.43) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL26259901 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL30018039 | 0.70 | MCL1 (0.47) | SMN1; SMN2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL24309031 | 0.70 | SIRT1 (0.51) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL14232434 | 0.68 | MAOB (0.42) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL27771980 | 0.68 | KDM4E (0.52) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| Iodide SCHEMBL10902480 | 0.68 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL11634342 | 0.67 | MEN1 (0.66) | SMN1; SMN2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL10903343 | 0.67 | PDGFRB (0.49) | SMN1; SMN2KDM4EALDH1A1NPC1HPGD | |
| SCHEMBL14231891 | 0.66 | MAOB (0.44) | RAB9AKDM4EALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022208382-A1 | NOVEL DIALKOXYNAPHTHO[2,3-C]FURAN-1(3H)-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE OR SARS-COV-2 INFECTION DISEASE, COMPRISING SAME | 동화약품주식회사 | 2022-10-06 | — | — | WO | claimed |
| WO-2022208382-A1 | NOVEL DIALKOXYNAPHTHO[2,3-C]FURAN-1(3H)-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE OR SARS-COV-2 INFECTION DISEASE, COMPRISING SAME | 동화약품주식회사 | 2022-10-06 | — | — | WO | disclosed |