Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460851 | 0.85 | SLC22A12 (0.48) | TFPI2SLC22A12ELANEASAH1KMO | |
| SCHEMBL260982 | 0.82 | SLC22A12 (0.54) | TFPI2SLC22A12ELANEASAH1KMO | |
| Hydrochloric Acid SCHEMBL30581596 | 0.80 | SLC22A12 (0.53) | TFPI2SLC22A12ELANEASAH1KMO | |
| SCHEMBL4423022 | 0.80 | SLC22A12 (0.55) | TFPI2SLC22A12ELANEASAH1KMO | |
| SCHEMBL5354143 | 0.78 | ELANE (0.51) | TFPI2SLC22A12ELANEASAH1KMO | |
| SCHEMBL496975 | 0.77 | ELANE (0.70) | TFPI2SLC22A12ELANEASAH1KMO | |
| SCHEMBL1087434 | 0.77 | CHEK1 (0.60) | TFPI2SLC22A12ELANEASAH1KMO | |
| Indazole Carboxamide SCHEMBL42505 | 0.77 | SLC22A12 (0.53) | TFPI2SLC22A12ELANEASAH1KMO | |
| SCHEMBL2025416 | 0.77 | SLC22A12 (0.56) | TFPI2SLC22A12ELANEASAH1KMO | |
| SCHEMBL29238955 | 0.76 | ELANE (0.68) | TFPI2SLC22A12ELANEASAH1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2013216579-A | METHOD FOR PRODUCING TRISUBSTITUTED INDAZOLEACRYLAMIDE DERIVATIVE | MITSUBISHI TANABE PHARMA CORP | 2013-10-24 | — | — | JP | disclosed |
| WO-2012005312-A1 | PROCESS FOR PREPARATION OF TRISUBSTITUTED INDAZOLEACRYLAMIDE DERIVATIVES | 田辺三菱製薬株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |