Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998064 | 0.87 | GRM5 (0.42) | FFAR1GRM5 | |
| SCHEMBL14562623 | 0.86 | FFAR1 (0.40) | FFAR1ERN1GRM5 | |
| SCHEMBL13248550 | 0.84 | FFAR1 (0.38) | FFAR1ERN1GRM5 | |
| SCHEMBL10236257 | 0.78 | FFAR1 (0.49) | FFAR1ERN1GRM5 | |
| SCHEMBL3004035 | 0.78 | HAO1 (0.40) | FFAR1ERN1GRM5 | |
| SCHEMBL13268158 | 0.75 | CYP3A4 (0.51) | — | |
| SCHEMBL278255 | 0.72 | ESR1 (0.56) | — | |
| SCHEMBL6766733 | 0.72 | FFAR1 (0.49) | FFAR1ERN1GRM5 | |
| Methyl Alcohol SCHEMBL28902013 | 0.71 | GRM5 (0.67) | FFAR1GRM5 | |
| SCHEMBL1809895 | 0.69 | FFAR1 (0.58) | FFAR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2546232-A1 | Diphenyl Substituted Alkanes | Merck Sharp & Dohme Corp. (US) | 2013-01-16 | — | — | EP | disclosed |
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK SHARP & DOHME CORP. | 2010-07-29 | — | — | US | disclosed |
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK SHARP & DOHME CORP. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | ALOX5, ALOX15, ALOX15B | FFAR1 73/4885ERN1 2084/4885GRM5 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.