Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 13/20 | 0.62 |
| ▸ | IGF1R | P08069 | 13/20 | 0.62 |
| ▸ | ALK | Q9UM73 | 13/20 | 0.62 |
| ▸ | EGFR | P00533 | 6/20 | 0.58 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.58 |
| ▸ | STK10 | O94804 | 2/20 | 0.58 |
| ▸ | ABL1 | P00519 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 2/20 | 0.58 |
| ▸ | FYN | P06241 | 2/20 | 0.58 |
| ▸ | FES | P07332 | 2/20 | 0.58 |
| ▸ | YES1 | P07947 | 2/20 | 0.58 |
| ▸ | HCK | P08631 | 2/20 | 0.58 |
| ▸ | ROS1 | P08922 | 2/20 | 0.58 |
| ▸ | FER | P16591 | 2/20 | 0.58 |
| ▸ | LTK | P29376 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 2/20 | 0.58 |
| ▸ | FRK | P42685 | 2/20 | 0.58 |
| ▸ | BTK | Q06187 | 2/20 | 0.58 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.58 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901099 | 0.90 | ALK (0.55) | INSRIGF1RALKEGFRPTK2 | |
| SCHEMBL18912630 | 0.80 | INSR (0.68) | INSRIGF1RALKEGFRPTK2 | |
| SCHEMBL18970177 | 0.80 | INSR (0.56) | INSRIGF1RALKEGFRPTK2 | |
| SCHEMBL30003588 | 0.80 | INSR (0.65) | INSRIGF1RALKEGFRPTK2 | |
| SCHEMBL26087590 | 0.80 | ALK (0.73) | INSRIGF1RALKEGFRPTK2 | |
| SCHEMBL15244473 | 0.80 | INSR (0.68) | INSRIGF1RALKEGFRPTK2 | |
| SCHEMBL30957983 | 0.79 | TTK (0.61) | INSRIGF1RALKEGFRCAMK2D | |
| SCHEMBL14180580 | 0.78 | INSR (0.52) | INSRIGF1RALKEGFRPTK2 | |
| SCHEMBL1044690 | 0.77 | EGFR (0.59) | INSRIGF1RALKEGFRPTK2 | |
| SCHEMBL1491729 | 0.77 | ALK (0.77) | INSRIGF1RALKEGFRPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022245085-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2022-11-24 | — | — | WO | disclosed |