Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.55 |
| ▸ | INSR | P06213 | 3/20 | 0.55 |
| ▸ | NPM1 | P06748 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | ULK1 | O75385 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 2/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.52 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.52 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.52 |
| ▸ | DCLK2 | Q8N568 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30020501 | 0.90 | INSR (0.62) | ALKINSRNPM1EGFRIGF1R | |
| SCHEMBL30340921 | 0.85 | IGF1R (0.54) | ALKINSREGFRIGF1RCDK2 | |
| SCHEMBL30340630 | 0.82 | MAPK10 (0.51) | ALKINSRNPM1EGFRIGF1R | |
| SCHEMBL28999541 | 0.81 | CTSC (0.55) | ALKINSRNPM1EGFRTNK2 | |
| SCHEMBL30340587 | 0.81 | CDK2 (0.55) | ALKINSRNPM1EGFRIGF1R | |
| SCHEMBL30039901 | 0.81 | EGFR (0.70) | ALKINSREGFRIGF1RCDK2 | |
| SCHEMBL12887598 | 0.81 | ULK1 (0.51) | ALKINSRNPM1ULK1IGF1R | |
| SCHEMBL28053990 | 0.81 | ALK (0.59) | ALKINSREGFRIGF1RCDK2 | |
| SCHEMBL30340484 | 0.80 | CDK2 (0.56) | ALKEGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340614 | 0.80 | ADRA2A (0.63) | EGFRIGF1RCDK2DYRK1BGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021197467-A1 | MULTI-TARGET ANTI-TUMOR COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华汇拓医药科技有限公司 | 2021-10-07 | — | — | WO | disclosed |