Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148112 | 1.00 | ACE (0.38) | ACETGM2TLR2PNMTPPARG | |
| SCHEMBL28512979 | 1.00 | ACE (0.38) | ACETGM2TLR2PNMTPPARG | |
| SCHEMBL30028093 | 0.92 | PNMT (0.36) | ACETGM2PNMTPPARGPPARA | |
| SCHEMBL2551608 | 0.86 | FOLH1 (0.45) | ACETGM2PNMTFOLH1 | |
| SCHEMBL2551604 | 0.86 | FOLH1 (0.45) | ACETGM2PNMTFOLH1 | |
| SCHEMBL28030109 | 0.86 | TLR2 (0.45) | ACETGM2TLR2PNMTFOLH1 | |
| SCHEMBL30028070 | 0.85 | NPC1 (0.31) | — | |
| SCHEMBL16695025 | 0.84 | MME (0.44) | ACETGM2PNMT | |
| SCHEMBL22804047 | 0.84 | MME (0.44) | ACETGM2PNMT | |
| SCHEMBL2537174 | 0.84 | MME (0.44) | ACETGM2PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304131-A | Alpha-carbonyl alkenyl ester compound, and preparation method and application thereof | 广州医科大学 | 2023-12-29 | — | — | CN | claimed |
| CN-118772247-A | PKal bicyclic peptide and application thereof in medicine | 西藏海思科制药有限公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2024153243-A1 | MODIFIED PEPTIDE AS TREM-1 INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-118359676-A | Modified peptides as Trem-1 inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-117304131-A | Alpha-carbonyl alkenyl ester compound, and preparation method and application thereof | 广州医科大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-113292430-B | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2022-11-29 | — | — | CN | disclosed |