SCHEMBL2537174

SCHEMBL2537174

NC(=O)CC[C@H](NC(=O)OCc1cccc2c1Cc1ccccc1-2)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 1/20 0.44
▸ ECE1 P42892 1/20 0.44
▸ KMT2A Q03164 1/20 0.43
▸ PNMT P11086 1/20 0.42
▸ TGM2 P21980 2/20 0.41
▸ ACE P12821 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22804047 1.00 MME (0.44) MMEECE1KMT2APNMTTGM2
SCHEMBL16695025 1.00 MME (0.44) MMEECE1KMT2APNMTTGM2
SCHEMBL2551608 0.92 FOLH1 (0.45) MMEECE1PNMTTGM2ACE
SCHEMBL2551604 0.92 FOLH1 (0.45) MMEECE1PNMTTGM2ACE
SCHEMBL21596245 0.91 PNMT (0.43) MMEECE1KMT2APNMTTGM2
SCHEMBL22804115 0.91 PNMT (0.43) MMEECE1KMT2APNMTTGM2
SCHEMBL9653586 0.91 PNMT (0.43) MMEECE1KMT2APNMTTGM2
SCHEMBL30940317 0.89 SIRT2 (0.43) PNMTTGM2ACE
SCHEMBL21315797 0.89 ACE (0.47) ECE1PNMTTGM2ACE
SCHEMBL28019287 0.89 ACE (0.47) ECE1PNMTTGM2ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO claimed
EP-4659764-A1 LINKER DRUG, AND PREPARATION METHOD AND USE OF ANTIBODY-DRUG CONJUGATE THEREOF Lepu Biopharma Co., Ltd. (CN) 2025-12-10 — — EP disclosed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO disclosed
EP-1613420-B1 METHOD FOR SELECTIVELY BINDING A SUBSTRATE TO SORBENTS BY WAY OF AT LEAST BIVALENT BONDS INSTRACTION GMBH (DE) 2015-05-13 — — EP disclosed
US-20110257028-A1 Method for selectively binding a substrate to sorbents by way of at least bivalent bonds INSTRACTION GMBH (DE) 2011-10-20 — — US disclosed
US-20060292569-A1 Method for selectively binding a substrate to sorbents by way of at least bivalent bonds INSTRACTION GMBH (DE) 2006-12-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257028-A1 Method for selectively binding a substrate to sorbents by way of at least bivalent bonds SPR, ABCG2, SHBG MME 583/4885ECE1 1995/4885KMT2A 2726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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