SCHEMBL2551604

SCHEMBL2551604

O=C(O)CCC(NC(=O)OCc1cccc2c1Cc1ccccc1-2)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 5/20 0.45
▸ TGM2 P21980 1/20 0.43
▸ MME P08473 1/20 0.43
▸ ECE1 P42892 1/20 0.43
▸ ACE P12821 1/20 0.42
▸ NAALAD2 Q9Y3Q0 3/20 0.42
▸ PNMT P11086 1/20 0.41
▸ GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2551608 1.00 FOLH1 (0.45) FOLH1TGM2MMEECE1ACE
SCHEMBL30502374 0.94 FOLH1 (0.40) FOLH1TGM2MMEECE1ACE
SCHEMBL16695025 0.92 MME (0.44) TGM2MMEECE1ACEPNMT
SCHEMBL22804047 0.92 MME (0.44) TGM2MMEECE1ACEPNMT
SCHEMBL2537174 0.92 MME (0.44) TGM2MMEECE1ACEPNMT
SCHEMBL30940317 0.91 SIRT2 (0.43) TGM2ACEPNMT
SCHEMBL1420538 0.90 CASP1 (0.46) MMEECE1PNMT
SCHEMBL30904667 0.90 CASP1 (0.46) MMEECE1PNMT
SCHEMBL30122530 0.90 CASP1 (0.46) MMEECE1PNMT
SCHEMBL2544343 0.90 CASP1 (0.46) MMEECE1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800876-A Fmoc-O-tert-butyl-L-glutamic acid production method 浙江汉诺化工科技有限公司 2024-04-02 — — CN claimed
EP-3473249-A1 CROSSLINKABLE DENDRIMERS Wayne State University (US) 2019-04-24 — — EP claimed
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 — — US claimed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 — — US claimed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 — — US claimed
EP-2552458-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Wayne State University (US) 2013-02-06 — — EP claimed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 — — WO claimed
CN-117800876-B Fmoc-O-tert-butyl-L-glutamic acid production method 浙江汉诺化工科技有限公司 2025-11-14 — — CN disclosed
CN-120118195-A Phage lyase analogues and uses thereof 上海多米瑞生物技术有限公司 2025-06-10 — — CN disclosed
CN-117800876-A Fmoc-O-tert-butyl-L-glutamic acid production method 浙江汉诺化工科技有限公司 2024-04-02 — — CN disclosed
CN-117800876-A Fmoc-O-tert-butyl-L-glutamic acid production method 浙江汉诺化工科技有限公司 2024-04-02 — — CN disclosed
CN-116970042-A Antiviral polypeptide analogues 上海多米瑞生物技术有限公司 2023-10-31 — — CN disclosed
US-11446238-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2022-09-20 — — US disclosed
WO-2019241903-A1 SYNTHETIC METHOD OF BIVALIRUNDIN SHANGHAI SPACE PEPTIDES PHARMACEUTICAL CO., LTD. (CN) 2019-12-26 — — WO disclosed
EP-3473249-A1 CROSSLINKABLE DENDRIMERS Wayne State University (US) 2019-04-24 — — EP disclosed
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 — — US disclosed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 — — US disclosed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 — — US disclosed
EP-2552458-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Wayne State University (US) 2013-02-06 — — EP disclosed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES PAM, UACA, FLT1 FOLH1 3470/4885TGM2 537/4885MME 4177/4885
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES UACA, PAM, JAK3 FOLH1 2813/4885TGM2 821/4885MME 4232/4885
US-11446238-B2 Injectable dendrimer hydrogel nanoparticles PAM, UACA, FLT1 FOLH1 3470/4885TGM2 537/4885MME 4177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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