Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 10/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20672216 | 1.00 | MAP3K5 (0.43) | MAP3K5GRM5GRM1HTTALOX15 | |
| SCHEMBL28643803 | 0.86 | MAP3K5 (0.53) | MAP3K5GRM5GRM1FGFR1ALDH1A1 | |
| SCHEMBL30029659 | 0.85 | MAP3K5 (0.42) | MAP3K5RIPK2 | |
| SCHEMBL20672223 | 0.85 | MAP3K5 (0.42) | MAP3K5RIPK2 | |
| SCHEMBL28656996 | 0.80 | MAP3K5 (0.53) | MAP3K5GRM5GRM1RIPK2ALDH1A1 | |
| SCHEMBL28649130 | 0.80 | GRM5 (0.45) | MAP3K5GRM5GRM1ALOX15RIPK2 | |
| SCHEMBL28658681 | 0.80 | TLR2 (0.44) | MAP3K5GRM5GRM1RIPK2ALDH1A1 | |
| SCHEMBL28654034 | 0.79 | MAP3K5 (0.48) | MAP3K5GRM5GRM1 | |
| SCHEMBL28648560 | 0.79 | GRM5 (0.44) | MAP3K5GRM5GRM1FGFR1 | |
| SCHEMBL28649133 | 0.79 | MAP3K5 (0.44) | MAP3K5GRM5GRM1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265443-B | Heterocyclic compounds as ASK inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2022-11-29 | — | — | CN | disclosed |