Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754834 | 1.00 | DTYMK (0.43) | DTYMKCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL30028551 | 0.79 | DDB1 (0.49) | DTYMKCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24754189 | 0.79 | DDB1 (0.49) | DTYMKCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24754836 | 0.78 | DDB1 (0.59) | DTYMK | |
| SCHEMBL30030025 | 0.78 | DDB1 (0.59) | DTYMK | |
| SCHEMBL24754832 | 0.76 | TLR9 (0.40) | DTYMKACHESIGMAR1 | |
| SCHEMBL30029738 | 0.76 | TLR9 (0.40) | DTYMKACHESIGMAR1 | |
| SCHEMBL16122889 | 0.74 | DTYMK (0.49) | DTYMKCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL4844156 | 0.72 | GPR119 (0.55) | DTYMKCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL15337783 | 0.67 | KRAS (0.47) | DTYMKCHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266248-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2022-12-22 | — | — | WO | disclosed |