SCHEMBL30029606

SCHEMBL30029606

C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H](CS)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 7/20 0.59
▸ IL23R Q5VWK5 6/20 0.57
▸ OPRD1 P41143 3/20 0.56
▸ OPRM1 P35372 2/20 0.56
▸ NPBWR1 P48145 2/20 0.55
▸ CCKBR P32239 2/20 0.55
▸ CCKAR P32238 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30028948 0.98 KISS1R (0.57) KISS1RIL23ROPRD1OPRM1NPBWR1
SCHEMBL29476584 0.93 KISS1R (0.60) KISS1RIL23ROPRD1OPRM1NPBWR1
SCHEMBL30264831 0.93 KISS1R (0.59) KISS1RIL23ROPRD1OPRM1NPBWR1
SCHEMBL29511018 0.93 KISS1R (0.58) KISS1RIL23ROPRD1OPRM1
SCHEMBL29511037 0.93 KISS1R (0.58) KISS1RIL23ROPRD1OPRM1
SCHEMBL31256969 0.92 KISS1R (0.63) KISS1ROPRD1OPRM1NPBWR1CCKBR
SCHEMBL31206256 0.90 KISS1R (0.55) KISS1RIL23ROPRD1OPRM1
SCHEMBL29476439 0.89 KISS1R (0.55) KISS1RIL23ROPRD1OPRM1NPBWR1
SCHEMBL29476441 0.89 KISS1R (0.55) KISS1RIL23ROPRD1OPRM1NPBWR1
SCHEMBL30264981 0.89 ACE (0.53) KISS1RIL23RNPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY IPSEN PHARMA SAS (FR) 2022-10-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY MC4R, MC1R, MC3R KISS1R 155/4885IL23R 301/4885OPRD1 359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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